Tag: Alzheimer

Insulin Resistance Unveils Obesity’s Connection to Neurodegeneration
Health

Insulin Resistance Unveils Obesity’s Connection to Neurodegeneration

Scientists, led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center, have unveiled a connection between obesity and neurodegenerative disorders like Alzheimer's disease. Their research, conducted on fruit flies, reveals that a high-sugar diet, characteristic of obesity, induces insulin resistance in the brain. This resistance hampers the removal of neuronal debris, elevating the risk of neurodegeneration. Published in the open-access journal PLOS Biology, the findings are poised to influence therapies aimed at mitigating the risk of neurodegenerative diseases. How Obesity Fuels Neurodegenerative Disorders Using Fruit Flies Although obesity is known to be a risk factor for neurodegenerative disorders like Alzheimer's disease and Parkinson's disease, exactly how one ...