Tag: Obesity

Higher BMI in Youth Impacts Future Cancer Risks
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Higher BMI in Youth Impacts Future Cancer Risks

High BMI at the time of conscription was linked to an increased risk of 17 malignancies, including lung, head and neck, brain, thyroid, esophageal, stomach, pancreatic, liver, colon, rectal, kidney, and bladder cancer, as well as malignant melanoma, leukemia, myeloma, and lymphoma (both Hodgkin's and non-Hodgkin's). For several cancer types, the risk was already enhanced with a BMI of 20-22.4, which is within the normal weight range (18.5-24.9). Cancers of the head and neck, esophagus, stomach, pancreas, liver, and kidney were among them, as were malignant melanoma and non-Hodgkin's lymphoma. "This suggests that the current definition of normal weight may be applicable primarily for older adults, while an optimal weight as a young adult is likely to ...
Obesity Linked to Poorer Rheumatoid Arthritis Flare Symptoms
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Obesity Linked to Poorer Rheumatoid Arthritis Flare Symptoms

RA is a systemic, autoimmune, inflammatory disorder that affects multiple joints in the body. The study will be presented at ACR Convergence 2023, () the annual meeting of the American College of Rheumatology. RA is usually treated with a combination of medications to relieve swelling and pain while regulating the immune system. Joint surgery to relieve pain and disability, including joint replacement, may also be considered when these nonsurgical methods fail to provide lasting benefit. Advertisement "If a person with RA is experiencing frequent flares, weight could be a contributing factor," said study principal investigator Vivian P. Bykerk, BSc, MD, FRCPC, a rheumatologist at HSS. "It may be helpful for patie...
Insulin Resistance Unveils Obesity’s Connection to Neurodegeneration
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Insulin Resistance Unveils Obesity’s Connection to Neurodegeneration

Scientists, led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center, have unveiled a connection between obesity and neurodegenerative disorders like Alzheimer's disease. Their research, conducted on fruit flies, reveals that a high-sugar diet, characteristic of obesity, induces insulin resistance in the brain. This resistance hampers the removal of neuronal debris, elevating the risk of neurodegeneration. Published in the open-access journal PLOS Biology, the findings are poised to influence therapies aimed at mitigating the risk of neurodegenerative diseases. How Obesity Fuels Neurodegenerative Disorders Using Fruit Flies Although obesity is known to be a risk factor for neurodegenerative disorders like Alzheimer's disease and Parkinson's disease, exactly how one ...